This comprehensive fact sheet analyzes Alzheimer’s disease (AD), the seventh leading cause of death in the United States and the most prevalent cause of dementia, which significantly hampers daily functioning. AD is marked by amyloid plaques, tau tangles, and the loss of neuronal connections. Symptoms start with memory issues, progressing to difficulties in language, reasoning, sensory processing, and recognition. Severe AD leads to complete dependence on others and substantial physical decline.

Addressing AD involves clinical trials and studies exploring causes, diagnosis, and management strategies, with participation from both affected individuals and healthy volunteers crucial for diverse and meaningful results. Current treatments target symptoms and behavioral issues, while ongoing research aims to develop interventions for the disease’s root causes. Caregiving for patients with AD is demanding, focusing on creating a supportive environment, managing behavioral changes, and ensuring caregiver well-being.

Reference: National Institute on Aging. Alzheimer’s Disease Fact Sheet. National Institute on Aging. Published January 14, 2019. Accessed April 3, 2024. https://www.nia.nih.gov/health/alzheimers-and-dementia/alzheimers-disease-fact-sheet