In a recent review, researchers analyzed the critical role of magnetic resonance imaging (MRI) in the early detection and management of dementia, focusing on both neurodegenerative and nondegenerative causes. MRI, especially the advanced 3T MRI, is vital in diagnosing dementia and its stages, including the evaluation of amyloid-related imaging abnormalities and patient selection for novel therapies like aducanumab.

Researchers categorized dementia based on its pathophysiological mechanisms into neurodegenerative and nondegenerative forms. MRI protocols, including different sequences, researchers noted, are critical for dementia assessment, detecting specific changes in brain regions that correlate with various dementia types. This understanding of MRI changes, along with other diagnostic tools and patient history, aids in the accurate diagnosis and management of dementia.

Reference: Živanović M, Aracki Trenkić A, Milošević V, et al. The role of magnetic resonance imaging in the diagnosis and prognosis of dementia. Biomol Biomed. 2023;23(2):209-224. doi: 10.17305/bjbms.2022.8085.