Authors of a review delved into the genetic underpinnings of Alzheimer’s disease (AD), the impact of dietary patterns on its prevention, and the socioeconomic challenges associated with dietary-based prevention strategies. Employing the MeSH search method and network analysis via VOS viewer, the findings underscore the significant impact of diets like the Mediterranean diet and DASH on reducing the risk of developing AD.

Notably, adherence to the Mediterranean diet resulted in a 53% reduction in AD risk, and similarly, following the MIND diet correlated with a considerable decrease in the incidence of AD. Omega-6 fatty acids, commonly found in nuts and fish, were highlighted for their role in clearing Beta-Amyloid, and vitamin D was noted for its potential to inhibit Aβ-induced apoptosis. Despite these promising links, the review acknowledges economic challenges, as the higher costs of these diet components could hinder the effectiveness of using dietary approaches for AD prevention.

Reference: Bhuiyan NZ, Hasan MK, Mahmud Z, Hossain MS, Rahman A. Prevention of Alzheimer’s disease through diet: An exploratory review. Metabol Open. 2023;20:100257. doi: 10.1016/j.metop.2023.100257.